The most significant and clearest difference between print and web design is the way that people view them. Browsing through a web page and seeing a graphic online is a drastically different experience compared to feeling a book in your hands, seeing an advertisement on the side of a bus or watching a billboard as you drive by.
Even if as the graphic is visually the same, the person viewing it is likely to interact with it differently according to how they view it. Seeing a physical copy is simple, and the extent of navigation might include unfolding a brochure or flipping a page. Web design may not be as user-friendly. Many different layouts and menu options must be evaluated and selected based on specific goals. Viewers’ screen sizes differ depending on what monitor or device they are using, and those size differences can affect how your design will come across.